Cyclopropylamine

Name: Cyclopropylamine

Also known as: Aminocyclopropane

Appearance: Colorless, transparent liquid

CAS Number: 765-30-0

Molecular formula: C3H7N

Molecular weight: 57.0944

Density (g/mL, 20/4℃): 0.824 g/mL

Melting point (°C): -50 °C

Boiling point (°C, atmospheric pressure): 49-50°C

Flash point (°F): −14°

Content: ≥99%;

Maximum single impurity: ≤0.3%

Total impurities: ≤1%

Moisture: ≤0.5%

This product is primarily prepared from γ-butyrolactone via ring-opening chlorination, esterification, cyclization, amination, and Hofmann degradation.

Ciprofloxacin is primarily used as an intermediate in organic synthesis and pharmaceutical synthesis. It can be employed to synthesize novel antibacterial agents belonging to the ciprofloxacin family, such as ciprofloxacin itself, enoxacin, sparfloxacin, and other related drugs.

In addition, cyclopropylamine is also an important intermediate for the synthesis of pesticides, plant protectants, and herbicides, such as cyclopropyl-triazine derivatives like 2-chloro-4,6-cyclopropyltriazine, cyclopropylamino herbicides, cyclopropylazine, and cyclopropyl cyanazine—cyclopropyl-based pesticides.